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Chemoenzymatic Synthesis of Trehalosamine, an Aminoglycoside Antibiotic and Precursor to Mycobacterial Imaging Probes
Trehalosamine (2-amino-2-deoxy-α,α-D-trehalose) is an aminoglycoside with antimicrobial activity against Mycobacterium tuberculosis, and it is also a versatile synthetic intermediate used to access imaging probes for mycobacteria. To overcome inefficient chemical synthesis approaches, we report a 2-...
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| Publicado no: | J Org Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6358420/ https://ncbi.nlm.nih.gov/pubmed/29973045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b00810 |
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