Deoxyfluoro-D-trehalose (FDTre) analogues as potential PET probes for imaging mycobacterial infection: rapid synthesis and purification, conformational analysis, and uptake by mycobacteria

Mycobacterium tuberculosis, the etiological agent of human tuberculosis, requires the non-mammalian disaccharide trehalose for growth and virulence. Recently, detectable trehalose analogues have gained attention as probes for studying trehalose metabolism and as potential diagnostic imaging agents f...

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Библиографические подробности
Опубликовано в: :Org Biomol Chem
Главные авторы: Rundell, Sarah R., Wagar, Zachary L., Meints, Lisa M., Olson, Claire D., O’Neill, Mara K., Piligian, Brent F., Poston, Anne W., Hood, Robin J., Woodruff, Peter J., Swarts, Benjamin M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026121/
https://ncbi.nlm.nih.gov/pubmed/27560008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01734g
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