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Intestine‐Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet‐Induced Liver Steatosis and Obesity

Murine hepatic carboxylesterase 2c (Ces2c) and the presumed human ortholog carboxylesterase 2 (CES2) have been implicated in the development of nonalcoholic fatty liver disease (NAFLD) in mice and obese humans. These studies demonstrated that Ces2c hydrolyzes triglycerides (TGs) in hepatocytes. Inte...

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Xehetasun bibliografikoak
Argitaratua izan da:Hepatol Commun
Egile Nagusiak: Maresch, Lisa Katharina, Benedikt, Pia, Feiler, Ursula, Eder, Sandra, Zierler, Kathrin A., Taschler, Ulrike, Kolleritsch, Stephanie, Eichmann, Thomas O., Schoiswohl, Gabriele, Leopold, Christina, Wieser, Beatrix I., Lackner, Caroline, Rülicke, Thomas, van Klinken, Jan, Kratky, Dagmar, Moustafa, Tarek, Hoefler, Gerald, Haemmerle, Guenter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357831/
https://ncbi.nlm.nih.gov/pubmed/30766961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1292
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