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Role of the Aryl Hydrocarbon Receptor in Carcinogenesis and Potential as an Anti-Cancer Drug Target

The aryl hydrocarbon receptor (AhR) was initially identified as the receptor that binds and mediates the toxic effects induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and structurally-related halogenated aromatics. Other toxic compounds including some polynuclear aromatic hydrocarbons (PAHs) a...

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Dades bibliogràfiques
Publicat a:Arch Toxicol
Autors principals: Kolluri, Siva Kumar, Jin, Un-Ho, Safe, Stephen
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357772/
https://ncbi.nlm.nih.gov/pubmed/28508231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-1981-2
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