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Role of the Aryl Hydrocarbon Receptor in Carcinogenesis and Potential as an Anti-Cancer Drug Target
The aryl hydrocarbon receptor (AhR) was initially identified as the receptor that binds and mediates the toxic effects induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and structurally-related halogenated aromatics. Other toxic compounds including some polynuclear aromatic hydrocarbons (PAHs) a...
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| Publicado no: | Arch Toxicol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6357772/ https://ncbi.nlm.nih.gov/pubmed/28508231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-1981-2 |
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