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Association score testing for rare variants and binary traits in family data with shared controls

Genome-wide association studies have been an important approach used to localize trait loci, with primary focus on common variants. The multiple rare variant–common disease hypothesis may explain the missing heritability remaining after accounting for identified common variants. Advances of sequenci...

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Bibliografiske detaljer
Udgivet i:Brief Bioinform
Main Authors: Saad, Mohamad, Wijsman, Ellen M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357552/
https://ncbi.nlm.nih.gov/pubmed/28968627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx107
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