Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment

Acute myeloid leukemia (AML) is an age-related disease that is highly dependent on the bone marrow (BM) microenvironment. With increasing age, tissues accumulate senescent cells, characterized by an irreversible arrest of cell proliferation and the secretion of a set of proinflammatory cytokines, ch...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Abdul-Aziz, Amina M., Sun, Yu, Hellmich, Charlotte, Marlein, Christopher R., Mistry, Jayna, Forde, Eoghan, Piddock, Rachel E., Shafat, Manar S., Morfakis, Adam, Mehta, Tarang, Di Palma, Federica, Macaulay, Iain, Ingham, Christopher J., Haestier, Anna, Collins, Angela, Campisi, Judith, Bowles, Kristian M., Rushworth, Stuart A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2019
Konular:
Myeloid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356984/
https://ncbi.nlm.nih.gov/pubmed/30401703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-04-845420
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