Synergistic effects of SHP2 and PI3K pathway inhibitors in GAB2-overexpressing ovarian cancer

The scaffold/adaptor growth factor receptor bound 2 (GRB2)-associated binding protein 2 (GAB2) is frequently amplified and/or overexpressed in primary high-grade serous ovarian cancers (HGSOCs). Here we investigate a novel treatment strategy by targeting SHP2 and PI3K signaling in HGSOCs with GAB2 a...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Am J Cancer Res
Asıl Yazarlar: Sun, Bowen, Jensen, Nathaniel R, Chung, Dongjun, Yang, Meixiang, LaRue, Amanda C, Cheung, Hiu Wing, Wang, Qi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2019
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356928/
https://ncbi.nlm.nih.gov/pubmed/30755818
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller