Gab2 Phosphorylation by RSK Inhibits Shp2 Recruitment and Cell Motility

The scaffolding adapter protein Gab2 (Grb2-associated binder) participates in the signaling response evoked by various growth factors and cytokines. Gab2 is overexpressed in several human malignancies, including breast cancer, and was shown to promote mammary epithelial cell migration. The role of G...

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Bibliographic Details
Main Authors: Zhang, Xiaocui, Lavoie, Genevieve, Fort, Loic, Huttlin, Edward L., Tcherkezian, Joseph, Galan, Jacob A., Gu, Haihua, Gygi, Steven P., Carreno, Sebastien, Roux, Philippe P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624252/
https://ncbi.nlm.nih.gov/pubmed/23401857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01353-12
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