Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models

Imaging of immunotherapy targets using positron emission tomography (PET) can allow for noninvasive monitoring of their dynamic expression and may allow for patient stratification in the future. Therefore, two tracers targeting CTLA-4, one a full antibody and the other a F(ab’)(2) fragment, were rad...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Ehlerding, Emily B, Lee, Hye Jin, Jiang, Dawei, Ferreira, Carolina A, Zahm, Christopher D, Huang, Peng, Engle, Jonathan W, McNeel, Douglas G, Cai, Weibo
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356917/
https://ncbi.nlm.nih.gov/pubmed/30755811
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