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Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models

Imaging of immunotherapy targets using positron emission tomography (PET) can allow for noninvasive monitoring of their dynamic expression and may allow for patient stratification in the future. Therefore, two tracers targeting CTLA-4, one a full antibody and the other a F(ab’)(2) fragment, were rad...

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Dettagli Bibliografici
Pubblicato in:Am J Cancer Res
Autori principali: Ehlerding, Emily B, Lee, Hye Jin, Jiang, Dawei, Ferreira, Carolina A, Zahm, Christopher D, Huang, Peng, Engle, Jonathan W, McNeel, Douglas G, Cai, Weibo
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356917/
https://ncbi.nlm.nih.gov/pubmed/30755811
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