IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer

Patients with epidermal growth factor receptor (EGFR) mutation-positive lung cancer show a dramatic response to EGFR-tyrosine kinase inhibitors (TKIs). However, acquired drug resistance eventually develops. This study explored the novel mechanisms related to TKI resistance. To identify the genes ass...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Wu, Shang-Gin, Chang, Tzu-Hua, Tsai, Meng-Feng, Liu, Yi-Nan, Hsu, Chia-Lang, Chang, Yih-Leong, Yu, Chong-Jen, Shih, Jin-Yuan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356910/
https://ncbi.nlm.nih.gov/pubmed/30609749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010036
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