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The Role of PIK3CA Mutations among Lung Adenocarcinoma Patients with Primary and Acquired Resistance to EGFR Tyrosine Kinase Inhibition

To understand the impact of PIK3CA mutations on clinical characteristics and treatment response to epidermal growth factor tyrosine kinase inhibitors (EGFR TKIs) of lung adenocarcinoma, we examined PIK3CA and EGFR mutations in lung adenocarcinoma patients, and analyzed their clinical outcomes. Surgi...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Wu, Shang-Gin, Chang, Yih-Leong, Yu, Chong-Jen, Yang, Pan-Chyr, Shih, Jin-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062358/
https://ncbi.nlm.nih.gov/pubmed/27734950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35249
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