Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK(+) Lung Cancer Patients with Poor Survival

Anaplastic lymphoma kinase (ALK) sequencing can identify resistance mechanisms and guide next-line therapy in ALK(+) non-small-cell lung cancer (NSCLC), but the clinical significance of other rebiopsy findings remains unclear. We analysed all stage-IV ALK(+) NSCLC patients with longitudinally assess...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Christopoulos, Petros, Dietz, Steffen, Kirchner, Martina, Volckmar, Anna-Lena, Endris, Volker, Neumann, Olaf, Ogrodnik, Simon, Heussel, Claus-Peter, Herth, Felix J., Eichhorn, Martin, Meister, Michael, Budczies, Jan, Allgäuer, Michael, Leichsenring, Jonas, Zemojtel, Tomasz, Bischoff, Helge, Schirmacher, Peter, Thomas, Michael, Sültmann, Holger, Stenzinger, Albrecht
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356563/
https://ncbi.nlm.nih.gov/pubmed/30669647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010124
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