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n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer

The farnesoid-X-receptor (FXR) protects against inflammation and cancer of the colon through maintenance of intestinal bile acid (BA) homeostasis. Conversely, higher levels of BA and cyclooxygenase-2 (COX-2) are risk factors for inflammation and cancer of the colon. In the United States, n-6 linolei...

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發表在:Nutrients
Main Authors: Romagnolo, Donato F., Donovan, Micah G., Doetschman, Tom C., Selmin, Ornella I.
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356359/
https://ncbi.nlm.nih.gov/pubmed/30650553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11010171
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