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A Villin-Driven Fxr Transgene Modulates Enterohepatic Bile Acid Homeostasis and Response to an n-6-Enriched High-Fat Diet

A diet high in n-6 polyunsaturated fatty acids (PUFAs) may contribute to inflammation and tissue damage associated with obesity and pathologies of the colon and liver. One contributing factor may be dysregulation by n-6 fatty acids of enterohepatic bile acid (BA) metabolism. The farnesoid X receptor...

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Publicat a:Int J Mol Sci
Autors principals: Wren, Spencer N., Donovan, Micah G., Selmin, Ornella I., Doetschman, Tom C., Romagnolo, Donato F.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659968/
https://ncbi.nlm.nih.gov/pubmed/33105708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217829
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