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Development and Characterization of a Mouse Model Overexpressing a Farnesoid-X-Receptor Transgene with Reduced Markers of Intestinal Inflammation (P08-122-19)
OBJECTIVES: The farnesoid-X-receptor (FXR) regulates bile acid (BA) homeostasis, protecting against colonic inflammation and cancer. Conversely, increased intestinal levels of BA and expression of cyclooxygenase-2 (COX-2) increase the risk of inflammation and cancer of the colon. Earlier studies fro...
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| Pubblicato in: | Curr Dev Nutr |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818934/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz044.P08-122-19 |
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