Molecular, Biological and Structural Features of V(L) CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells

Microtubules are important drug targets in tumor cells, owing to their role in supporting and determining the cell shape, organelle movement and cell division. The complementarity-determining regions (CDRs) of immunoglobulins have been reported to be a source of anti-tumor peptide sequences, indepen...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Girola, Natalia, Resende-Lara, Pedro T., Figueiredo, Carlos R., Massaoka, Mariana H., Azevedo, Ricardo A., Cunha, Rodrigo L. O. R., Polonelli, Luciano, Travassos, Luiz R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355703/
https://ncbi.nlm.nih.gov/pubmed/30740361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00025
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