AC‐1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model

Antibody‐derived peptides modulate functions of the immune system and are a source of anti‐infective and antitumor substances. Recent studies have shown that they comprise amino acid sequences of immunoglobulin complementarity‐determining regions, but also fragments of constant regions. V(H) CDR3 of...

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Bibliografski detalji
Izdano u:FEBS Open Bio
Glavni autori: Rabaça, Aline N., Arruda, Denise C., Figueiredo, Carlos R., Massaoka, Mariana H., Farias, Camyla F., Tada, Dayane B., Maia, Vera C., Silva Junior, Pedro I., Girola, Natalia, Real, Fernando, Mortara, Renato A., Polonelli, Luciano, Travassos, Luiz R.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011487/
https://ncbi.nlm.nih.gov/pubmed/27642552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12080
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