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Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma()

Bi-allelic inactivation of the VHL gene on chromosome 3p is the characteristic feature in most clear cell renal cell carcinomas (ccRCC). Frequent gene alterations were also identified in SETD2, BAP1 and PBRM1, all of which are situated on chromosome 3p and encode histone/chromatin regulators. The re...

詳細記述

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書誌詳細
出版年:Neoplasia
主要な著者: Bihr, Svenja, Ohashi, Riuko, Moore, Ariane L., Rüschoff, Jan H., Beisel, Christian, Hermanns, Thomas, Mischo, Axel, Corrò, Claudia, Beyer, Jörg, Beerenwinkel, Niko, Moch, Holger, Schraml, Peter
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355619/
https://ncbi.nlm.nih.gov/pubmed/30660076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.12.006
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