Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma()

Bi-allelic inactivation of the VHL gene on chromosome 3p is the characteristic feature in most clear cell renal cell carcinomas (ccRCC). Frequent gene alterations were also identified in SETD2, BAP1 and PBRM1, all of which are situated on chromosome 3p and encode histone/chromatin regulators. The re...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Bihr, Svenja, Ohashi, Riuko, Moore, Ariane L., Rüschoff, Jan H., Beisel, Christian, Hermanns, Thomas, Mischo, Axel, Corrò, Claudia, Beyer, Jörg, Beerenwinkel, Niko, Moch, Holger, Schraml, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355619/
https://ncbi.nlm.nih.gov/pubmed/30660076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.12.006
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