Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma()

Bi-allelic inactivation of the VHL gene on chromosome 3p is the characteristic feature in most clear cell renal cell carcinomas (ccRCC). Frequent gene alterations were also identified in SETD2, BAP1 and PBRM1, all of which are situated on chromosome 3p and encode histone/chromatin regulators. The re...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neoplasia
Päätekijät: Bihr, Svenja, Ohashi, Riuko, Moore, Ariane L., Rüschoff, Jan H., Beisel, Christian, Hermanns, Thomas, Mischo, Axel, Corrò, Claudia, Beyer, Jörg, Beerenwinkel, Niko, Moch, Holger, Schraml, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Neoplasia Press 2019
Aiheet:
Original article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355619/
https://ncbi.nlm.nih.gov/pubmed/30660076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.12.006
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