Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma()

Bi-allelic inactivation of the VHL gene on chromosome 3p is the characteristic feature in most clear cell renal cell carcinomas (ccRCC). Frequent gene alterations were also identified in SETD2, BAP1 and PBRM1, all of which are situated on chromosome 3p and encode histone/chromatin regulators. The re...

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Dettagli Bibliografici
Pubblicato in:Neoplasia
Autori principali: Bihr, Svenja, Ohashi, Riuko, Moore, Ariane L., Rüschoff, Jan H., Beisel, Christian, Hermanns, Thomas, Mischo, Axel, Corrò, Claudia, Beyer, Jörg, Beerenwinkel, Niko, Moch, Holger, Schraml, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2019
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355619/
https://ncbi.nlm.nih.gov/pubmed/30660076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.12.006
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