Multicenter Population Pharmacokinetic Study of Colistimethate Sodium and Colistin Dosed as in Normal Renal Function in Patients on Continuous Renal Replacement Therapy

Intravenous colistimethate sodium (CMS) is used to treat infections with multiresistant Gram-negative bacteria. Optimal dosing in patients undergoing continuous renal replacement therapy (CRRT) is unclear. In a prospective study, we determined CMS and colistin pharmacokinetics in 10 critically ill p...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Leuppi-Taegtmeyer, Anne B., Decosterd, Laurent, Osthoff, Michael, Mueller, Nicolas J., Buclin, Thierry, Corti, Natascia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355613/
https://ncbi.nlm.nih.gov/pubmed/30478168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01957-18
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