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Population Pharmacokinetics of Atazanavir in Patients with Human Immunodeficiency Virus Infection

Atazanavir (ATV) is a new azapeptide protease inhibitor recently approved and currently used at a fixed dose of either 300 mg once per day (q.d.) in combination with 100 mg ritonavir (RTV) or 400 mg q.d. without boosting. ATV is highly bound to plasma proteins and extensively metabolized by CYP3A4....

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Detalhes bibliográficos
Main Authors: Colombo, Sara , Buclin, Thierry, Cavassini, Matthias, Décosterd, Laurent A., Telenti, Amalio, Biollaz, Jérôme, Csajka, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635184/
https://ncbi.nlm.nih.gov/pubmed/16940065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00098-06
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