Population pharmacokinetic modelling to quantify the magnitude of drug-drug interactions between amlodipine and antiretroviral drugs

PURPOSE: Drug-drug interactions (DDIs) with antiretroviral drugs (ARVs) represent an important issue in elderly people living with HIV (PLWH). Amlodipine is a commonly prescribed antihypertensive drug metabolized by CYP3A4, thus predisposed to a risk of DDIs. Guidance on the management of DDIs is mo...

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Detalhes bibliográficos
Publicado no:Eur J Clin Pharmacol
Main Authors: Courlet, Perrine, Guidi, Monia, Alves Saldanha, Susana, Cavassini, Matthias, Stoeckle, Marcel, Buclin, Thierry, Marzolini, Catia, Decosterd, Laurent A., Csajka, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Pharmacokinetics and Disposition
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184532/
https://ncbi.nlm.nih.gov/pubmed/33452585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-03060-2
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