Development and validation of a multiplex UHPLC‐MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV

The widespread use of highly active antiretroviral treatments has dramatically changed the prognosis of people living with HIV (PLWH). However, such treatments have to be taken lifelong raising issues regarding the maintenance of both therapeutic effectiveness and long‐term tolerability. Recently ap...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Mass Spectrom
المؤلفون الرئيسيون: Courlet, Perrine, Alves Saldanha, Susana, Cavassini, Matthias, Marzolini, Catia, Choong, Eva, Csajka, Chantal, Günthard, Huldrych F., André, Pascal, Buclin, Thierry, Desfontaine, Vincent, Decosterd, Laurent Arthur
التنسيق: Artigo
اللغة:Inglês
منشور في: John Wiley and Sons Inc. 2020
الموضوعات:
Research Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317362/
https://ncbi.nlm.nih.gov/pubmed/32160389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.4506
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