Mutations in cdsA and pgsA Correlate with Daptomycin Resistance in Streptococcus mitis and S. oralis

We investigated the ability of several recent clinical viridans group streptococci (VGS) bloodstream isolates (Streptococcus mitis/S. oralis subgroup) from daptomycin (DAP)-naive patients to develop DAP resistance in vitro. All strains rapidly developed high-level and stable DAP resistance. Substitu...

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Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Tran, Truc T., Mishra, Nagendra N., Seepersaud, Ravin, Diaz, Lorena, Rios, Rafael, Dinh, An Q., Garcia-de-la-Maria, Cristina, Rybak, Michael J., Miro, Jose M., Shelburne, Samuel A., Sullam, Paul M., Bayer, Arnold S., Arias, Cesar A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355606/
https://ncbi.nlm.nih.gov/pubmed/30509945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01531-18
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