Mutations in cdsA and pgsA Correlate with Daptomycin Resistance in Streptococcus mitis and S. oralis

We investigated the ability of several recent clinical viridans group streptococci (VGS) bloodstream isolates (Streptococcus mitis/S. oralis subgroup) from daptomycin (DAP)-naive patients to develop DAP resistance in vitro. All strains rapidly developed high-level and stable DAP resistance. Substitu...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Tran, Truc T., Mishra, Nagendra N., Seepersaud, Ravin, Diaz, Lorena, Rios, Rafael, Dinh, An Q., Garcia-de-la-Maria, Cristina, Rybak, Michael J., Miro, Jose M., Shelburne, Samuel A., Sullam, Paul M., Bayer, Arnold S., Arias, Cesar A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355606/
https://ncbi.nlm.nih.gov/pubmed/30509945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01531-18
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