Mutations in cdsA and pgsA Correlate with Daptomycin Resistance in Streptococcus mitis and S. oralis

We investigated the ability of several recent clinical viridans group streptococci (VGS) bloodstream isolates (Streptococcus mitis/S. oralis subgroup) from daptomycin (DAP)-naive patients to develop DAP resistance in vitro. All strains rapidly developed high-level and stable DAP resistance. Substitu...

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發表在:Antimicrob Agents Chemother
Main Authors: Tran, Truc T., Mishra, Nagendra N., Seepersaud, Ravin, Diaz, Lorena, Rios, Rafael, Dinh, An Q., Garcia-de-la-Maria, Cristina, Rybak, Michael J., Miro, Jose M., Shelburne, Samuel A., Sullam, Paul M., Bayer, Arnold S., Arias, Cesar A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
主題:
Mechanisms of Resistance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355606/
https://ncbi.nlm.nih.gov/pubmed/30509945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01531-18
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