Perturbations of Phosphatidate Cytidylyltransferase (CdsA) Mediate Daptomycin Resistance in Streptococcus mitis/oralis by a Novel Mechanism

Streptococcus mitis/oralis is an important pathogen, causing life-threatening infections such as endocarditis and severe sepsis in immunocompromised patients. The β-lactam antibiotics are the usual therapy of choice for this organism, but their effectiveness is threatened by the frequent emergence o...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Mishra, Nagendra N., Tran, Truc T., Seepersaud, Ravin, Garcia-de-la-Maria, Cristina, Faull, Kym, Yoon, Alex, Proctor, Richard, Miro, Jose M., Rybak, Michael J., Bayer, Arnold S., Arias, Cesar A., Sullam, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365703/
https://ncbi.nlm.nih.gov/pubmed/28115347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02435-16
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