Modeling Prevention of Malaria and Selection of Drug Resistance with Different Dosing Schedules of Dihydroartemisinin-Piperaquine Preventive Therapy during Pregnancy in Uganda

Dihydroartemisinin-piperaquine (DHA-PQ) is under study for intermittent preventive treatment during pregnancy (IPTp), but it may accelerate selection for drug resistance. Understanding the relationships between piperaquine concentration, prevention of parasitemia, and selection for decreased drug se...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wallender, Erika, Zhang, Nan, Conrad, Melissa, Kakuru, Abel, Muhindo, Mary, Tumwebaze, Patrick, Kajubi, Richard, Mota, Daniel, Legac, Jennifer, Jagannathan, Prasanna, Havlir, Diane, Kamya, Moses, Dorsey, Grant, Aweeka, Francesca, Rosenthal, Philip J., Savic, Rada M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355581/
https://ncbi.nlm.nih.gov/pubmed/30530597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01393-18
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