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Misactivation of Hedgehog signaling causes inherited and sporadic cancers

The Hedgehog pathway is critical for the development of diverse organs. Misactivation of the Hedgehog pathway can cause developmental abnormalities and cancers, including medulloblastoma, the most common pediatric brain tumor, and basal cell carcinoma, the most common cancer in the United States. He...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Raleigh, David R., Reiter, Jeremy F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355229/
https://ncbi.nlm.nih.gov/pubmed/30707108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120850
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