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Misactivation of Hedgehog signaling causes inherited and sporadic cancers

The Hedgehog pathway is critical for the development of diverse organs. Misactivation of the Hedgehog pathway can cause developmental abnormalities and cancers, including medulloblastoma, the most common pediatric brain tumor, and basal cell carcinoma, the most common cancer in the United States. He...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Raleigh, David R., Reiter, Jeremy F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355229/
https://ncbi.nlm.nih.gov/pubmed/30707108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120850
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