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Misactivation of Hedgehog signaling causes inherited and sporadic cancers

The Hedgehog pathway is critical for the development of diverse organs. Misactivation of the Hedgehog pathway can cause developmental abnormalities and cancers, including medulloblastoma, the most common pediatric brain tumor, and basal cell carcinoma, the most common cancer in the United States. He...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Raleigh, David R., Reiter, Jeremy F.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355229/
https://ncbi.nlm.nih.gov/pubmed/30707108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120850
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