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Transcription factor mutations as a cause of familial myeloid neoplasms
The initiation and evolution of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are driven by genomic events that disrupt multiple genes controlling hematopoiesis. Human genetic studies have discovered germline mutations in single genes that instigate familial MDS/AML. The best under...
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| 發表在: | J Clin Invest |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355228/ https://ncbi.nlm.nih.gov/pubmed/30707109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120854 |
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