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Blood disease–causing and –suppressing transcriptional enhancers: general principles and GATA2 mechanisms

Intensive scrutiny of human genomes has unveiled considerable genetic variation in coding and noncoding regions. In cancers, including those of the hematopoietic system, genomic instability amplifies the complexity and functional consequences of variation. Although elucidating how variation impacts...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Bresnick, Emery H., Johnson, Kirby D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616255/
https://ncbi.nlm.nih.gov/pubmed/31289032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000378
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