A structural model of the immune checkpoint CD160–HVEM complex derived from HDX-mass spectrometry and molecular modeling

CD160 is a T cell coinhibitory molecule that interacts with the herpes virus entry mediator (HVEM) on antigen-presenting cells to provide an inhibitory signal to T cells. To date, the structure of CD160 and its complex with HVEM are unknown. Here, we have identified the fragments of CD160 interactin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Kuncewicz, Katarzyna, Spodzieja, Marta, Sieradzan, Adam, Karczyńska, Agnieszka, Dąbrowska, Katarzyna, Dadlez, Michał, Speiser, Daniel E., Derre, Laurent, Rodziewicz-Motowidło, Sylwia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355189/
https://ncbi.nlm.nih.gov/pubmed/30728903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26570
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