Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1

Mechanisms of treatment resistance in head and neck squamous cell carcinoma (HNSCC) are not well characterized. In this study, HNSCC tumors from a cohort of prospectively enrolled subjects on an ongoing tissue banking study were divided into those that persisted or recurred locoregionally (n=23) and...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ow, Thomas J., Fulcher, Cory D., Thomas, Carlos, Broin, Pilib Ó, López, Andrea, Reyna, Denis E., Smith, Richard V., Sarta, Catherine, Prystowsky, Michael B., Schlecht, Nicolas F., Schiff, Bradley A., Rosenblatt, Gregory, Belbin, Thomas J., Harris, Thomas M., Childs, Geoffrey C., Kawachi, Nicole, Guha, Chandan, Gavathiotis, Evripidis
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355180/
https://ncbi.nlm.nih.gov/pubmed/30728900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26563
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