Apoptosis Signaling Molecules as Treatment Targets in Head and Neck Squamous Cell Carcinoma

OBJECTIVES: To evaluate BCL-2 family signaling molecules in head and neck squamous cell carcinoma (HNSCC) and examine the ability of therapeutic agents with variable mechanisms of action to induce apoptosis in HNSCC cells. METHODS: mRNA expression of BAK, BAX, BCL2, BCL2L1, and MCL1 were measured in...

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Publicado en:Laryngoscope
Main Authors: Ow, Thomas J., Thomas, Carlos, Fulcher, Cory D., Chen, Jianhong, López, Andrea, Reyna, Denis E., Prystowsky, Michael B., Smith, Richard V., Schiff, Bradley A., Rosenblatt, Gregory, Belbin, Thomas J., Harris, Thomas M., Childs, Geoffrey C., Kawachi, Nicole, Schlecht, Nicolas F., Gavathiotis, Evripidis
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142150/
https://ncbi.nlm.nih.gov/pubmed/31894587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.28441
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