Apoptosis Signaling Molecules as Treatment Targets in Head and Neck Squamous Cell Carcinoma

OBJECTIVES: To evaluate BCL-2 family signaling molecules in head and neck squamous cell carcinoma (HNSCC) and examine the ability of therapeutic agents with variable mechanisms of action to induce apoptosis in HNSCC cells. METHODS: mRNA expression of BAK, BAX, BCL2, BCL2L1, and MCL1 were measured in...

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書誌詳細
出版年:Laryngoscope
主要な著者: Ow, Thomas J., Thomas, Carlos, Fulcher, Cory D., Chen, Jianhong, López, Andrea, Reyna, Denis E., Prystowsky, Michael B., Smith, Richard V., Schiff, Bradley A., Rosenblatt, Gregory, Belbin, Thomas J., Harris, Thomas M., Childs, Geoffrey C., Kawachi, Nicole, Schlecht, Nicolas F., Gavathiotis, Evripidis
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142150/
https://ncbi.nlm.nih.gov/pubmed/31894587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.28441
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