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Exploring chromatin hierarchical organization via Markov State Modelling
We propose a new computational method for exploring chromatin structural organization based on Markov State Modelling of Hi-C data represented as an interaction network between genomic loci. A Markov process describes the random walk of a traveling probe in the corresponding energy landscape, mimick...
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| Foilsithe in: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Public Library of Science
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355033/ https://ncbi.nlm.nih.gov/pubmed/30596637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006686 |
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