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Multi-scale chromatin state annotation using a hierarchical hidden Markov model

Chromatin-state analysis is widely applied in the studies of development and diseases. However, existing methods operate at a single length scale, and therefore cannot distinguish large domains from isolated elements of the same type. To overcome this limitation, we present a hierarchical hidden Mar...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Marco, Eugenio, Meuleman, Wouter, Huang, Jialiang, Glass, Kimberly, Pinello, Luca, Wang, Jianrong, Kellis, Manolis, Yuan, Guo-Cheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385569/
https://ncbi.nlm.nih.gov/pubmed/28387224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15011
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