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Discovery and characterization of chromatin states for systematic annotation of the human genome

A plethora of epigenetic modifications have been described in the human genome and shown to play diverse roles in gene regulation, cellular differentiation, and the onset of disease. While some modifications have been linked with activity levels of different functional elements, their combinatorial...

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Détails bibliographiques
Auteurs principaux: Ernst, Jason, Kellis, Manolis
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919626/
https://ncbi.nlm.nih.gov/pubmed/20657582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1662
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