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Discovery and characterization of chromatin states for systematic annotation of the human genome

A plethora of epigenetic modifications have been described in the human genome and shown to play diverse roles in gene regulation, cellular differentiation, and the onset of disease. While some modifications have been linked with activity levels of different functional elements, their combinatorial...

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Detalhes bibliográficos
Main Authors: Ernst, Jason, Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919626/
https://ncbi.nlm.nih.gov/pubmed/20657582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1662
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