Linear Polyethylenimine-DNA Nanoconstruct for Corneal Gene Delivery

Purpose: This study investigated the efficiency and potential toxicity of a linear 22-kDa polyethylenimine (PEI)–DNA nanoconstruct for delivering genes to corneal cells and the effects of PEI nitrogen-to-DNA phosphate (N:P) ratio on gene transfer efficiency in vitro and in vivo. Methods: A gel retar...

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Detaylı Bibliyografya
Yayımlandı:J Ocul Pharmacol Ther
Asıl Yazarlar: Rodier, Jason T., Tripathi, Ratnakar, Fink, Michael K, Sharma, Ajay, Korampally, Madhuri, Gangopadhyay, Shubhra, Giuliano, Elizabeth A., Sinha, Prashant R., Mohan, Rajiv R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc., publishers 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354610/
https://ncbi.nlm.nih.gov/pubmed/30699061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2018.0024
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