Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

BACKGROUND: Small fiber neuropathy (SFN) is a severe and disabling chronic pain syndrome with no causal and limited symptomatic treatment options. Mechanistically based individual treatment is not available. We report an in-vitro predicted individualized treatment success in one therapy-refractory C...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Namer, Barbara, Schmidt, Diana, Eberhardt, Esther, Maroni, Michele, Dorfmeister, Eva, Kleggetveit, Inge Petter, Kaluza, Luisa, Meents, Jannis, Gerlach, Aaron, Lin, Zhixin, Winterpacht, Andreas, Dragicevic, Elena, Kohl, Zacharias, Schüttler, Jürgen, Kurth, Ingo, Warncke, Torhild, Jorum, Ellen, Winner, Beate, Lampert, Angelika
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354557/
https://ncbi.nlm.nih.gov/pubmed/30503201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.042
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