Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors

Human pluripotent stem cells (hPSCs) offer the opportunity to generate neuronal cells, including nociceptors. Using a chemical-based approach, we generated nociceptive sensory neurons from HUES6 embryonic stem cells and retrovirally reprogrammed induced hPSCs derived from fibroblasts. The nociceptiv...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Eberhardt, Esther, Havlicek, Steven, Schmidt, Diana, Link, Andrea S., Neacsu, Cristian, Kohl, Zacharias, Hampl, Martin, Kist, Andreas M., Klinger, Alexandra, Nau, Carla, Schüttler, Jürgen, Alzheimer, Christian, Winkler, Jürgen, Namer, Barbara, Winner, Beate, Lampert, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618592/
https://ncbi.nlm.nih.gov/pubmed/26321143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.010
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