RNF216 Regulates the Migration of Immortalized GnRH Neurons by Suppressing Beclin1-Mediated Autophagy

RNF216, encoding an E3 ubiquitin ligase, has been identified as a causative gene for Gordon Holmes syndrome, characterized by ataxia, dementia, and hypogonadotropic hypogonadism. However, it is still elusive how deficiency in RNF216 leads to hypogonadotropic hypogonadism. In this study, by using GN1...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Endocrinol (Lausanne)
मुख्य लेखकों: Li, Fangfang, Li, Dengfeng, Liu, Huadie, Cao, Bei-Bei, Jiang, Fang, Chen, Dan-Na, Li, Jia-Da
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2019
विषय:
Endocrinology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354547/
https://ncbi.nlm.nih.gov/pubmed/30733708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00012
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