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The relationship between pulsatile GnRH secretion and cAMP production in immortalized GnRH neurons

In perifused immortalized GnRH neurons (GT1–7), simultaneous measurements of GnRH and cAMP revealed that the secretory profiles for both GnRH and cAMP are pulsatile. An analysis of GnRH and cAMP pulses in 16 independent experiments revealed that 25% of pulses coincide. Inversion of the peak and nadi...

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Autori principali: Frattarelli, John L., Krsmanovic, Lazar Z., Catt, Kevin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118589/
https://ncbi.nlm.nih.gov/pubmed/21447787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00081.2011
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