Neurokinin B Causes Acute GnRH Secretion and Repression of GnRH Transcription in GT1–7 GnRH Neurons

Genetic studies in human patients with idiopathic hypogonadotropic hypogonadism (IHH) identified mutations in the genes that encode neurokinin B (NKB) and the neurokinin 3 receptor (NK3R). However, determining the mechanism whereby NKB regulates gonadotropin secretion has been difficult because of c...

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Dades bibliogràfiques
Autors principals: Glidewell-Kenney, Christine A., Shao, Paul P., Iyer, Anita K., Grove, Anna M. H., Meadows, Jason D., Mellon, Pamela L.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589675/
https://ncbi.nlm.nih.gov/pubmed/23393128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1271
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