Androgen Receptor Repression of GnRH Gene Transcription

Alterations in androgen levels lead to reproductive defects in both males and females, including hypogonadotropic hypogonadism, anovulation, and infertility. Androgens have been shown to down-regulate GnRH mRNA levels through an androgen receptor (AR)-dependent mechanism. Here, we investigate how an...

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Autores principales: Brayman, Melissa J., Pepa, Patricia A., Berdy, Sara E., Mellon, Pamela L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2012
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248321/
https://ncbi.nlm.nih.gov/pubmed/22074952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1015
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