Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma

BACKGROUND: An immunosuppressive microenvironment is critical for cancer initiation and progression. Whether interferon alpha (IFNα) can suppress immune and cancer cells and its involved mechanism still remain largely elusive. METHODS: We examine the expression of interferon alpha/beta receptor-1 (I...

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Udgivet i:Br J Cancer
Main Authors: Ma, Hailong, Yang, Wenyi, Zhang, Liming, Liu, Shuli, Zhao, Mei, Zhou, Ge, Wang, Lizhen, Jin, Shufang, Zhang, Zhiyuan, Hu, Jingzhou
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353953/
https://ncbi.nlm.nih.gov/pubmed/30555157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0352-y
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