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Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening

Fibrous scaffolds are used for bone tissue engineering purposes with great success across a variety of polymers with different physical and chemical properties. It is now evident that the correct degree of curvature promotes increased cytoskeletal tension on osteoprogenitors leading to osteogenic di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ozdemir, Tugba, Bowers, Daniel T., Zhan, Xiang, Ghosh, Debashis, Brown, Justin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353928/
https://ncbi.nlm.nih.gov/pubmed/30700820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37554-y
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